Once a polygonal mesh is extracted from volumetric data, any imperfections need to be resolved and validated. These imperfections might includes holes (each surface needs to be topologically closed), intersecting polygons and singularities. I won't know how much editing will be needed before I try the surface extraction with a few sets of parameters.
It looks like MeshLab might be a good surface editing tool:
Science 18 April 2008 Vol 320, Issue 5874 has a wonderful article about the geometry of music, how "many musical terms can be understood as expressing symmetries of n-dimensional space, where each dimension represents a voice in the score. Identifying—gluing together—points related by these symmetries produces exotic mathematical spaces (orbifolds) that subsume a large number of geometric models previously proposed."
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